IVI’s disease-specific models currently focus on the relative value of drug therapies and do not include other types of intervention (surgery, for example). To model the relative efficacy of different treatments or interventions, we must first know how the various options compare to one another, which requires reliable clinical evidence from randomized control trials (RCTs). Because of FDA drug approval requirements, RCTs are much more common for drug therapies than for other technologies (e.g. devices) or interventions (e.g. specific surgical techniques). IVI hopes to eventually include all types of interventions, but significant gaps in clinical evidence must first be addressed.