IVI-NSCLC Value Model
A Flexible Modeling Platform for Lung Cancer
Oncology is an area of immense clinical need and a primary driver of healthcare spending, making it a prime target for assessment of the value of available medical interventions. Of the many forms of cancer, lung cancer is the leading cause of cancer-related deaths worldwide.(1) The American Cancer Society estimates that of the 1,735,000 new cancer cases in the U.S. in 2018, 13.5% will be lung cancer. NSCLC accounts for an estimated 85% of lung cancer cases and comprises adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.(2)
IVI’s first oncology-specific Open-Source Value Platform (OSVP) model focuses on non-small cell lung cancer (NSCLC). Specifically, the IVI-NSCLC model examines the value of sequential treatment strategies for patients with epidermal growth factor receptor positive (EGFR+) NSCLC, which accounts for 8% of new NSCLC cases.(3)
How Does the IVI-NSCLC Model Work?
The IVI-NSCLC model is an open-source simulation model that decision-makers can use to assess the value of different sequences of treatment for non-small cell lung cancer (NSCLC). Specifically, the IVI-NSCLC model provides information on expected health benefits, risks and costs for patients with EGFR+ NSCLC.
Incorporating the Patient Perspective
See how we worked with patients and other stakeholders to build Version 1 of the IVI-RA Value Tool.
Application in the Real World
Learn about the mechanics of the IVI-RA model, which serves as the engine for the IVI-RA Value Tool, and see specific examples of how it can be used.
Review IVI-RA Model Detailed Methodology
Click here to learn more about the technical details on how the IVI-RA model is constructed.
Get Started with the IVI-NSCLC Value Model
The IVI-NSCLC Value Tool is an easy-to-use web-based interface designed to help healthcare decision-makers use the IVI-NSCLC model to evaluate treatment strategies for EGFR+ NSCLC.
Two versions of the IVI-NSCLC Value Tool are available.
- The Basic interface is designed to provide a streamlined experience for general audience users with limited expertise.
- The Advanced interface is designed for users with clinical or technical expertise and provides complete control over all modeling.
IVI-NSCLC Value Tools are optimized for use with Google Chrome.
RESOURCES
The IVI-NSCLC model, part of the Open-Source Value Project (OSVP), was created, developed, and is owned by Precision Health Economics LLC (now PRECISIONheor) and is licensed to IVI Foundation, Inc. for its use in connection with redefining how value of pharmaceutical treatment is assessed. In keeping with IVI’s philosophy, this includes sharing and distribution of source code, data and parameter inputs, and any additional materials and technical documentation supporting open use, distribution, and adaptation of the model with attribution to the model developers.
In addition, any work performed by IVI based on the IVI-NSCLC model is conducted as part of the OSVP and is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license visit: https://creativecommons.org/licenses/by/4.0/.